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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 8
First page : ( 3886) Last page : ( 3890)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00668.1

Optimizations of Spray Drying Process Parameters for Anthocephalus cadamba (Roxb.) leaves extract by using Aerosil as Spray Drying Agent

Gunjal Sachinkumar D.*, Shirolkar Satish V.

Department of Pharmaceutics, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018, India

*Corresponding Author E-mail: sachin13802004@gmail.com

Online published on 24 December, 2019.

Abstract

The objective of this work was to optimize spray drying process parameters for Anthocephalus cadamba leaves aqueous extract. The stickiness of aqueous extract and hygroscopicity of powder obtained are major problems associated with spray drying process. In present work, aerosil was used as spray drying agents. The inlet air temperatures, Feed flow rate and aerosil concentrations were treated as independent variables. Moisture content, % yield, bulk density, hygroscopicity, time required for solubilization were determined to evaluate the effects of various spray drying processing parameters on cadamba leaves extract powder properties. Increases in inlet air temperature caused an increase in % yield. Increases in inlet air temperature also caused decrease in moisture content, bulk density and hygroscopicity of the powder obtained. Increases in aerosil concentration caused an increase in yield and a decrease in moisture content, bulk density, hygroscopicity, time required for solubilization.

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Keywords

Anthocephalus cadamba, Optimization, Spray drying, Aqueous extract, Aerosil.

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