Evaluation of the Antimicrobial activity of Cumin oil mediated silver nanoparticles on Oral microbes Vignesh S.1, Anitha Roy2,*, Kumar S. Rajesh2, Lakshmi T.2 1Under Graduate Student, Dept.of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai, India 2Associate Professor, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu, India *Corresponding Author E-mail: anitharoy2015@gmail.com
Online published on 24 December, 2019. Abstract Aim The aim of the study was to synthesise cumin oil mediated silver nanoparticles and to evaluate its effect on oral microbes. Introduction Silver nanoparticles have been assessed for their catalytic, various optical, magnetic andantibacterial properties. It has a large application in the various fields such as photography, biosensor, biomolecular detection and in cosmetics. Materials and Methods The silver nanoparticles were prepared initially using cumin oil and confirmed both visually as well as spectrophotometrically. The antimicrobial activity of the cumin oil mediated silver nanoparticles were then evaluated by agar well diffusion method and the zone of inhibition was recorded against oral pathogens such as Streptococcus mutans, Staphylococcus aureus and E.fecalis. Results The cumin oil mediated silver nanoparticles showed dose dependent antimicrobial activity with very good zone of inhibition against the tested oral pathogens. Conclusion This study prove that cumin oil mediated silver nanoparticles can be used for the control of infections caused byStreptococcus mutans, Staphylococcus aureus and E.fecalis. Top Keywords Silver nanoparticles, anti microbial activity, cumin oil. Top |