Anti-inflammatory Activity of Turmeric Oil Mediated Silver Nanoparticles Das Anubhav1, Roy Anitha2,*, Rajeshkumar S.2, Lakshmi T.2 1Graduate Student, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Tamil Nadu, India 2Associate Professor, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Tamil Nadu, India *Corresponding Author E-mail: anitharoy2015@gmail.com
Online published on 24 December, 2019. Abstract Background Curcuma longa is a medicinal plant commonly known as turmeric and well known for its medicinal properties. Curcumin, the main constituent of turmeric,. Curcumin is responsible for the biological activities of turmeric. Curcumin has potent anti-inflammatory activity. Aim In the present study, antiinflammatory activity of turmeric oil mediated silver nanoparticle was Carried out. Materials and Methods Turmeric oil was obtained from Synthite Industries Limited, Kerala as a gift sample and silver nanoparticle was prepared using Turmeric oil. The synthesized nanoparticles solution was preliminarily characterized by using UV-visible spectroscopy. The color change in reaction mixture (Silver nitrate solution + turmeric oil) was recorded by visual observation. The results were recorded for the graphical analysis. Results The greatest effect of AgNPs (150 μg/mL) was found to be more than standard diclofenac sodium. Conclusion It may be concluded from this study that turmeric oil mediated silver nanoparticles can be used as potential source of anti inflammatory agent. Top Keywords Curcuma longa, curcuminoids, anti-inflammatory, Bovine Serum albumin, albumin denaturation assay. Top |