Synthesis and Pharmacological Activity of Some 2-[6-(Phenyl) 2-Thio 1, 3Oxazin-3yl] Amino Benzothiazole Derivatives Joshi G. S.*, Asnani A. J. 1Researcher, Dadasaheb Balpande College of Pharmacy, Nagpur-440037, India 2Professor, J. L. Chaturvedi College of Pharmacy, Nagpur-440016, India, ajasnani7@gmail.com *Corresponding Author E-mail: jsgunja@gmail.com
Online published on 8 August, 2019. Abstract Some new hydrazino group substituted benzothiazole derivatives have been synthesized and their characterization were identified on the basis of melting point range, Rf values, IR and 1H NMR spectral analysis. The derivatives were screened for anti-inflammatory (Carrageenan-induced paw edema test in rats), analgesic (Hot plate method) and anticonvulsant (Electric shock method) activities inflammatory, analgesic and anticonvulsant activities. The derivatives exhibited significant to moderate anti-inflammatory analgesic and anticonvulsant activities. Top Keywords Hydrazino, Benzothiazole, Anti-inflammatory activity, Analgesic activity, Anticonvulsant activity. Top |