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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 6
First page : ( 2677) Last page : ( 2681)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00447.5

Determination the levels of Bone Morphogentic Protein-2, P-selectin, substance P in β-Thalassemia major in Iraqi patients

Hussein Noor Ali*, Al-Harbi Hussein Jassim

Biology Department, College of Science, University of Babylon, Iraq

*Corresponding Author E-mail: msc.noor30@gmail.com

Online published on 8 August, 2019.

Abstract

The current study aimed to assess BMP-2, P-selectin, substance-p in β-thalassemia major patients in Babylon Province (Iraq), by enrolling individual of Arab ancestry. A total of 70 beta-thalassemia major patients and 30 normal individual were enrolled Family history. All patients were blood transfusion depend with age mean (14.1±0.7years). On the other hand the selected control do not have history of family for thalassemia and doesn't have any disease with mean age (15.6±1.2years). The result revealed significant decrease in BMP-2 in betathalassemia major patients, and significant increase in P-selectin, substance P in beta-thalassemia major patients.

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Keywords

Beta-thalassemia major, BMP-2, P-selectin, substance-P, ferritin.

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