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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 6
First page : ( 2645) Last page : ( 2647)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00442.6

Effect of Liquid Media Height on the Pressure Drop during Production of Antibiotics in Bioreactor

Kumar S.1,*, Arora A.2, Chandra H.3

1Research Scholar, Department of Mechanical Engineering, Bhilai Institute of Technology, Durg, Chhattisgarh, India

2Professor, Department of Mechanical Engineering, Bhilai Institute of Technology, Durg, Chhattisgarh, India

3Associate Professor, Department of Mechanical Engineering, Vishwavidyalaya Engineering College, Sarguja University, Ambikapur, Chhattisgarh, India

*Corresponding Author E-mail: saurabhkumar2002@gmail.com

Online published on 8 August, 2019.

Abstract

Three phase gas-liquid-solid systems are widely used by the pharmaceutical industries for the production of antibiotics such as patulin, penicillin, bacitracin etc. for which immobilized cell system or biofilms are used. During the process immobilized cells are fluidized in the liquid media using air. The present paper investigates regarding the dependency of the pressure drop on the height of liquid media present in the fluidizer.

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Keywords

Immobilized cell, biofilm, fluidization, antibiotics, bioreactor.

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