Synthesis and Characterization New Heterocyclic Compounds derivatives from Vanillin Abd Al Hussain Hutham Abd Ali1,*, Abbas Sawsan Khudhair2 1Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Kerbala, Iraq 2Department of Chemistry, College of Sciences, University of Kerbala, Iraq *Corresponding Author E-mail: huthamabd15@yahoo.com
Online published on 8 August, 2019. Abstract In this article, some new heterocyclic derivatives, for example pyrimidine and pyrazoles were synthesized by reaction vanillin with paracetamol utilizing KOH as a catalyst to synthase 3-(4-hydroxy-3-methoxyphenyl)-N-(4hydroxyphenyl)acrylamide(1). The compound (1) on react with Sodium azide, hydrazine, urea, and thiourea in the existence of acetic acid or KOH and ethanol as a catalyst to give (2, 3, 4, 5) compounds. The reaction monitors by TLC. All synthesized compounds have been distinguished by melting point, IR, 1H.NMR spectroscopy. Top Keywords Vanillin, paracetamol, heterocyclic. Top |