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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 2
First page : ( 693) Last page : ( 698)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00123.9

Effects of Dual-Task Training with different Intensity of Aerobic Exercise on Cognitive Function and Neurotrophic Factors in Chronic Stroke Patients

Kim Tae-Gon1, Bae Sea-Hyun2, Kim Kyung-Yoon2,*

1Department of Physical Therapy, Eunhye Hospital, 5–5, Geobukseongongwon 2-gil, Yeosu-si, Chonnam, 59676, Republic of Korea

2Department of Physical Therapy, College of Health and Welfare, Dongshin University 185, Gunjae-ro, Naju-si, Chonnam, Republic of Korea

*Corresponding Author E-mail: redbead7@daum.net

Online published on 18 April, 2019.

Abstract

Background/Objectives

The present study aimed to investigate the effects of dual-task training with different intensity of aerobic exercise on cognitive function (MMSE-K, Trail making test, and Stroop test) and neurotrophic factors (BDNF, IGF-1) in chronic stroke patients.

Methods/Statistical analysis

The subjects were 27 stroke patients who met the study selection criteria, and were divided according to screening tests into the following: group I (low-intensity aerobic exercise plus dual-task training, n=9), group II (moderate-intensity aerobic exercise plus dual-task training, n=9), and group III (high-moderate-intensity aerobic exercise plus dual-task training, n=9). Subjects performed training 5 times a week, a total of 30 times in 6 weeks.

Finding

The results of the study showed that moderate-intensity aerobic exercise (p<.01) and high-intensity aerobic exercise (p<.001) showed significant differences between after training (p<.001). Significant differences between the groups were found after training, with a difference in MMSE-K between group I and III (p<.001) and between group II and III (p<.01). A significant difference was found between the groups in the Trail Making Test and the Stroop test (p<.001), with a difference after training between group I and III (p<.001) and between group II and III (p<.01). In addition, a significant difference was found between the groups in BDNF and IGF-1 levels (p<.001), with a difference between group I and III (p<.001) and between group II and III (p<.05).

Improvements/Applications

Therefore, the present study found that the effectiveness of cognitive rehabilitation for stroke patients can be enhanced by using differentiated aerobic exercise rather than limited desktop activity

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Keywords

Dual task training, Aerobic exercise, Intensity, Cognitive function, Neurotrophic factor.

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