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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 10
First page : ( 4709) Last page : ( 4713)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00811.4

Evaluation of Gastroesophageal Reflux by Transabdominal Ultrasound in Adults: Focused on Subdiaphragmatic Esophageal Length, His angle, Moment of Reflux

Park Ki-Tae1, Jeong Youn-Sin1, Seoung Youl-Hun2

1Department of Radiology, Hanaro Clinic, Daejeon, 34411, Republic of Korea

2Department of Radiology Science, Cheongju University, Republic of Korea

Corresponding Author E-mail: hanarokt@outlook.com, jeonghanaro@gmail.com, radimage@naver.com

Online published on 24 December, 2019.



The purpose of this retrospective study was to evaluate factors affecting the diagnosis of gastroesophageal reflux (GER) using transabdominal ultrasound.

Methods/Statistical analysis

The patient group comprised of 18 adults with upper endoscopy results of Los Angeles (LA)-classifications A or above, while the control group included of 68 adults with normal upper endoscopy. The ultrasonography was used to measure the subdiaphragmatic esophageal length, gastroesophageal angle (His angle) and real-time ultrasonography at the moment of reflux.


The subdiaphragmatic esophageal length was 29.2±3.6 mm in the control group, and 22.7±3.2 mm in the patient group. The results showed statistically significant difference between the two groups. The cut-off value for the subdiaphragmatic esophageal length was 25.1 mm. Sensitivity and specificity were 88.9% and 86.9% respectively. The gastroesophageal angle measured 121.9±12.3° in the control group and 141.5±8.8° in the patient group. The cut-off value of 134.6° showed a sensitivity of 83.3% and specificity of 83.8%. There were statistically significant differences (p = 0.001) during real-time ultrasonography with reflux in 77.8% of the patient group and 10.3% in the control group. The real-time ultrasonography showed a sensitivity of 77.8%, specificity of 89.7%, positive predictive value of 66.7% and negative predictive value 93.8%.


This study suggests that the transabdominal ultrasound used in measuring the subdiaphragmatic part of the esophageal length, His angle and real-time ultrasonography to be good predictive factors in diagnosing GER disease. Therefore, a medical examination with a noninvasive procedure such as transabdominal ultrasound may be a useful procedure in predicting gastroesophageal disorders.



Gastroesophageal Reflux, Ultrasound, Esophageal Length, His Angle, Real-time Ultrasonography.


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