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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 1
First page : ( 445) Last page : ( 460)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00081.7

Neermulli Kudineer-A Classical Polyherbal Decoction in Siddha System of Medicine

Kumar A. Rajendra1, Muthukumar N. J.2, Faridha A.3,*

1Research Officer (S), I/C, Scientist-II, Siddha Regional Research Institute, Chellaperumal Street, Kuyavarpalayam, Puducherry-605013

2Director General, Central Council for Research in Siddha, (Ministry of AYUSH, Govt. of India), Govt. Anna Hospital Campus, Arumbakkam, Chennai-600106

3Senior Research Fellow (S), Siddha Regional Research Institute, Chellaperumal street, Kuyavarpalayam, Puducherry-605013

*Corresponding Author E-mail: fari.jas@gmail.com

Online published on 16 March, 2019.


Siddha system of medicine enunciates the usage of herbs and herbal formulations since time immemorial. The advancement in the application of ethno-medicine has been increased globally. The treatment approach in Siddha methodology primarily commences with the administration of “Kudineer” i.e. decoction as a first line of treatment for many diseases. Neermulli Kudineer (NMK) is one such polyherbal decoction enumerated in Siddha medical literatures for various ailments. The usage of Neermulli Kudineer is prevalent among the traditional Siddha clinicians in the treatment of diseases such as oedema, urolithiasis, anuria, dysuria, urinary tract infections, oliguria, ascites, inflammation, obesity, renal hypertension and even in the management of certain infertility cases. Thus Neermulli Kudineer has gained its iconic significance as a potent diuretic in Siddha system of medicine. Diuretics in general, play a pivotal role in renal diseases, cardiovascular diseases and liver diseases. As NMK is a natural herbal diuretic in Siddha medicine, it may overcome the adverse effects of conventional diuretics. The current review is aimed to substantiate the traditional efficacy of ingredients of NMK through Siddha literatures and various scientific literatures. The pharmacological review of the ingredients of this decoction revealed their excellency in antiurolithiatic, diuretic, hepatoprotective, nephroprotective, hematinic, anti-inflammatory, lithotriptic, analgesic, antioxidant, antimicrobial, immunomodulatory, antihyperglycemic and lipid lowering activities. Hence the traditional use of Neermulli Kudineer is validated with available literatures.



Neermulli Kudineer, polyherbal, decoction, diuretic, Siddha medicine, literatures, pharmacological activity.


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