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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 9
First page : ( 3819) Last page : ( 3825)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00700.X

Correlation of Internet Addiction Disorder with Level of Stress and BDNF Gene (Val66Met) Polymorphism among Medical Students in Malaysia

Al-Hatamleh Mohammad Ahmed Issa1, Al-Shajrawi Omar Mahmoud1, Khan Saif Ullah2, Nadeem Muhammad Ilyas1, Simbak Nordin Bin1, Latif Ahmad Zubaidi A.1, Baig Atif Amin1,*, Ariff Tengku Mohammad3,**

1Faculty of Medicine, Universiti Sultan Zainal Abidin, Kuala Terengganu, Malaysia

2Factuly of Applied Social Sciences, Universiti Sultan Zainal Abidin, Kuala Terengganu, Malaysia

3Institute for Community (Health) Development and Quality of Life (I-CODE), Universiti Sultan Zainal Abidin, Kuala Terengganu, Malaysia

*Corresponding Author E-mail: atifamin@unisza.edu.my


Online published on 20 December, 2018.


Medical students who are suffering a stressful life have high chance to internet addiction disorder (IAD), as they spend most of their time inappropriately on the internet. Medical students are assumed to be among the most exposed group in any community towards stress. Deferent factors effect on level of stress, variant of BDNF gene may thus play a key role in genetic predispositions to stress. This review article hypothesised that there is a correlation between IAD, level of stress, and BDNF gene (Met66Val) polymorphism; medical students with high levels of stress and IAD may carry BDNF met-allele. This review article Aimed to create researcher's interest further to generate a future database that helps in the academics and education about disadvantages and distress of IAD, besides emphasising the empowerment of balanced life among medical students in Malaysia besides the increasing level of health and academic performance.



Internet addiction, Stress, Oxidative stress, Medical students, BDNF.


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