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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 9
First page : ( 3799) Last page : ( 3801)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00696.0

Amlodipine Causes Ecchymosis and Hematuria

Selman Selman M.*

University of Babylon, College of Medicine, Department of Pharmacology, Babylon, Iraq

*Corresponding Author E-mail: selmanmohammed14@uobabylon.edu.iq

Online published on 20 December, 2018.


A 48-year-old male, was diagnosed with essential hypertension and was treated with amlodipine 5 mg once a day, and candesartan 16 mg once a day. After two months of starting of treatment by amlodipine, the patient complained flat, brownish black patches and some time associated with small local edema on different parts of body. There was no history of any other illness during the above period. General and clinical examinations revealed no abnormalities. Clotting time, bleeding time, fibrinogen level, and platelet function test are normal. The antihypertensive therapy changed from amlodipine to another class of antihypertension drugs. Over a period of 4 weeks, the ecchymosis and hematuria resolved.



Amlodipine, Ecchymosis, Hematuria.


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