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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 8
First page : ( 3514) Last page : ( 3522)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00650.9

Applications of Metal-Organic Frameworks (MOFs) to Separation Analytical Techniques

Mansour Oussama1,*, Kawas Ghufran1, Rasheed Mouhammad Abu2, Sakur Amir Alhaj2

1Pharmaceutical Chemistry and Quality Control Dept. Faculty of Pharmacy, Al Andalus University, Syria

2Analytical and Food Chemistry Department Faculty of Pharmacy, University of Aleppo, Syria

*Corresponding Author E-mail: mansouroussama@yahoo.fr

Online published on 31 October, 2018.


Metal-Organic Frameworks (MOFs) are a variety of advanced micro-porous coordination materials that have high surface area, permanent porosity and a distinct semi-organic structure. These characteristics make it possible to use MOFs as a potential sorbents for many important applications; especially, analytical chemistry. In this review we will focus on the utilization of these coordination networks in analytical chemistry applications, and more accurately, in separation techniques including; sampling processes, solid phase extraction (SPE) and solid phase micro-extraction (SPME), liquid and gas chromatography. These techniques showed a significant improvements in sensitivity and selectivity parameters by using MOFs, which make them attractive as advanced separation media to meet many analytical challenges; especially in environmental, biological, and industrial fields. However, more studies should be performed to detect more possible metal-organic structures and reveal all potential features and advantages of these micro-porous materials to analytical chemistry.



Metal-Organic Frameworks (MOFs), Metal-Organic Coordination Networks (MOCNs), sorbents, separation techniques, chromatography.


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