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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 8
First page : ( 3437) Last page : ( 3439)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00634.0

One-Step Multicomponent Synthesis of 2,6-Dihydro-2,6-Diimino-4,8- Diphenoxy Pyrimido [2,1-B] [1,3] Oxazine-3,7-Dicarbonitrile and its Derivatives

Chidrawar Anil B.*

Department of Chemistry, Degloor College, S.R.T.M.U, Degloor, Nanded, India-431717

*Corresponding Author E-mail: anilchidrawar74@gmail.com

Online published on 31 October, 2018.


A mixture of BMMM, urea and phenol/4-bromo phenol/4-chloro phenol/4-methoxy phenol/4-nitro phenol on reflux with dimethyl formamide solvent in presence of K2CO3 for 5–6 hours gives 2,6-dihydro-2,6-diimino-4,8-diphenoxypyrimido [2,1-b] [1,3] oxazine-3,7-dicarbonitrile and its derivatives respectively. The synthesized compounds were characterized by elemental analysis and spectral data.



BMMM, urea, 4-substituted phenols, dimethyl formamide, K2CO3.


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