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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 7
First page : ( 3113) Last page : ( 3118)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00571.1

Determination of Triterpenoids in Some Lamiaceae Species

Shanaida Mariia1,*, Pryshlyak Antonina2, Golembiovska Olena3

1Department of Pharmacognosy with Medical Botany, I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine

2Department of Human Anatomy, I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine

3Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine

*Corresponding Author E-mail: shanayda-mi@ukr.net

Online published on 31 October, 2018.

Abstract

The present study was designated to analyze the triterpenoids presence and content in ethanolic extracts of three Lamiaceae species gathered under the condition of West Podillya region (Ukraine). The presence of triterpenoids in Dracocephalum moldavica L., Lophanthus anisatus (Nutt.) Benth and Satureja hortensis L. aerial parts was proved by the identification procedures. The chemical composition and content of triterpenoids was investigated using HPLC. The revealed triterpenoids were the derivates of α-amyrin (ursolic, euscaphic and tormentic acids), β-amyrin (oleanilic acid) and lupane (lupeole and betulin). It was established that high concentrations of ethanol (96% and 70%) removed from plants more considerable amount of triterpenoids than 50% ethanol. The comparative HPLC-analysis showed the significant differences in content of pentacyclic triterpenoids in the investigated species. Ursolic and euscaphic acids were the most abundant components in the ethanoic extracts of all three plants while the content of tormentic acid and lupeol were the smallest. The obtained data can be used in the planning of pharmacological studies and in the chemotaxonomy of Lamiaceae Family.

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Keywords

Dracocephalum moldavicaLophanthus anisatusSatureja hortensis, pentacyclic triterpenoids, HPLC.

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