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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 7
First page : ( 3087) Last page : ( 3090)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00567.X

Stability indicating Method Development and Validation of Telmisartan and Ramipril by UV Spectrophotometry

Sonia K.1,*, Dr. Nappinnai M.2, Dr. Panneerselvam P.3

1Ph.D Scholar, CL Baid Mehta College of Pharmacy, Chennai, Tamil Nadu

2Professor, Surya School of Pharmacy, Chennai, Tamil Nadu

3Professor, CL Baid Mehta College of Pharmacy, Chennai, Tamil Nadu

*Corresponding Author E-mail:

Online published on 31 October, 2018.

Abstract

A simple, highly validated, accurate and more precise simultanesous UV Spectrophotometric method has been developed for the simultaneous estimation of Telmisartan and Ramipril in pharmaceutical dosage form. It exhibits the λmax ot Telmisartan at 255nm whereas Ramipril shows at 210nm.this method shows good linearity, accuracy, precision, limit of detection and limit of quantification with respect to forced degradation studies it can be applied to routine simultanesous estimation in pharmaceutical dosage form.

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Keywords

Telmisartan, Ramipril, Forced degradation, method development and validation.

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