Cytotoxicity and Antimicrobial Activity of Ipomoea batatas Chakraborty Pritha, Sharma Shivani, Chakraborty Soumita, Siddapurand Ashwini, Abraham Jayanthi* 109A Microbial Biotechnology Lab, School of Biosciences and Technology (SBST), VIT University, Vellore-632014, Tamil Nadu, India *Corresponding Author E-mail: jayanthi.abraham@gmail.com
Online published on 31 October, 2018. Abstract Ipomoea batatas popularly known as the sweet potato is a dicotyledonous plant that belongs to the Convolvulaceaefamily. Sweet potato tuber is a widely used source of nutrients. As not much work has been done on leaves, this study was undertaken to explore phytochemical, antioxidant, antimicrobial and anticancer activity of sweet potato leaves through different screening tests. Antimicrobial activities were studied by agar well diffusion method against nine clinical pathogens. The total antioxidant capacity was evaluated by the DPPH assay and followed by cytotoxicity activity on humanosteosarcoma (MG 63) cell line, using methanol and hexane extract as well as Thin Layer Chromatography (TLC) was performed for the separation of different components of the extract. Volatile extract of Sweet potato leaves were also interpreted using Gas Chromatography and Mass spectrometry. Both the extract showed good antimicrobial and antioxidant activity, whereas both methanol and hexane extract showed moderate anticancer activity. Sweet potato leaves are suitable for further clinical approach in near future. Top Keywords Sweet potato, Antimicrobial activity, Antioxidant activity, Cytotoxicity. Top |