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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 6
First page : ( 2695) Last page : ( 2700)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00498.5

Alzheimer disease and a potential role of herbs-A review

Velraj Malarkodi*, Lavaniya N.

Department of Pharmacognosy, School of Pharmaceutical Science, Vels University (VISTAS), Velan Nagar, P V Vaithiyalingam Road, Pallavaram, Chennai-117

*Corresponding Author E-mail: malarkodisanna@gmail.com

Online published on 24 August, 2018.

Abstract

Alzheimer's disease is a neurodegenerative disease and it is one among the ten major diseases of leading causes of death which cannot be prevented, cured or slowed. AD is found to effect elderly people above 60 years and about 1-in 5 people are diagnosed to be effected by AD all over the world according to 2017 senses. It is the cause of 60–70% of dementia and premature senility (having or showing the weakness of disease of old age, especially a loss of mental faculties) and these are the cause for the disabilities in later life. AD is characterised by decline in cognitive function of the brain. These is caused due to the accumulation of β-amyloid protein and tau protein inside the neuron and leading to the death of neuron. The pharmacotherapy is focussed on symptomatic benefits and to slowing down the disease progression, not the permanent cure the main objective of these review is brief discussion about the Alzheimer disease and herbs active role towards AD as plants give natural treatment with lesser or no side effects. The herbs having essential neuroprotective, antioxidant and anticholinesterase properties are found to play a potential role in Alzheimer's.

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Keywords

Alzheimer disease (AD), Neurodegenerative, Dementia, Premature senility, Cognitive function, Neuroprotective, Anticholinesterase.

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