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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 5
First page : ( 1734) Last page : ( 1736)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00322.0

Detection of hemolysin and gelatinase in uropathological Escherichia coli

Niyas F. Mariyam1,*, Gopinath P2,**

1Bachelor of Dental Surgery, Department of Microbiology, Saveetha Dental College and Hospital, Chennai, Tamilnadu, India

2Assistant Professor, Department of Microbiology, Saveetha Dental College and Hospital, Chennai, Tamilnadu, India

*Corresponding Author E-mail: marlog7494@gmail.com

**gopu.myco@gmail.com

Online published on 21 August, 2018.

Abstract

Background

Urinary tract infection(UTI) is a major public health concernin developing countries. Most UTIs are caused by E.coli, accounting for up to 90% of community acquired UTIs.

Materials and methods

A total of 20 clinical isolates of uropathological E.coli(UPEC) were subjected for antibiotic sensitivity pattern and virulence assay such as hemolysin and gelatinase production.

Results

100% of our isolates were hemolysin producers, whereas none of the isolates were positive for gelatinase production.

Conclusion

Hemolysin might play a crucial role in initiation of UTI in hospitalized individuals. Drug resistance can also be the factor for the treatment failure cases.

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Keywords

Hemolysin, Gelatinase, Enterotoxigenic, uropathology.

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