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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 4
First page : ( 1619) Last page : ( 1623)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00301.3

Hot-Melt Extrusion Technology in the Emerging Pharma Field

Naaz Shaik, Tippavajhala Vamshi Krishna*

Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India

*Corresponding Author E-mail: krissrcm@gmail.com

Online published on 24 July, 2018.


After the plastic industry, now in Pharmaceutical industry hot melt extrusion (HME) technology has emerged and has made its way for the easy development of the pharmaceutical products due to its severe advantages like free of solvents, faster processing technology, operation in simple and continuous process, and high degree of automation, are few among them over to the other conventional methods. Day by day the interest on HME technology has been increasing due to its promising approach towards the drug delivery systems. The gradual increase in the patents of HME technology will enlighten us the need of it in this field of medicines. This article mainly reviews the general design and construction of hot melt extruder along with the advantages, disadvantages and applications of the HME.



Hot melt extrusion, Solubility enhancement, Formulation development.


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