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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 4
First page : ( 1298) Last page : ( 1300)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00241.X

Anthelmintic activity of methanolic bark extract of Buchanania axillaris (Desr.)

Babu N. Dora1, Kodithala Saritha2,*, Murali R3, Srinivasan N3

1Mother Teresa Pharmacy College, Sanketika Nagar, Sathupally, Khammam District, Telangana

2Department of Pharmacognosy, KVK College of Pharmacy, Surmaiguda (V), Hayathnagar (M), RR Dist.-501512, TS, India

3Department of Pharmacy, FEAT, Annamalai University, Annamalai Nagar, Chidambaram. 608002

*Corresponding Author E-mail: saritha.kodithala@gmail.com

Online published on 24 July, 2018.

Abstract

Buchanania axillaris Desr is the most significant genus in the family Anacardiaceae, which is commonly known as Peddamoriin India. This study evaluates anthelmintic activity of methanol extract of Buchanania axillaris Desr on Indian adult earthworms, Pheretimaposthuma (annelid). Bark was extracted by using soxhlet apparatus. Phytochemical screening of crude extracts showed the presence of steroids, alkaloids, tannins, flavonoids, carbohydrates and glycosides Various concentrations (25, 50, 100mg/ml) of crude extracts were tested for Anthelmintic activity when involved the determination of the time of paralysis and time of death of worms. The activity was compared with standard piperazine citrate. The methanolic extract shows significant activity when compared to the standard piperazine citrate. The paralysis and death time is 50, 31, 17 and 76, 52, 34 minutes respectively at concentrations 25, 50 and 100mg/ml. whereas these are 31, 18, 10 and 63, 41, 22 minutes for piperazine citrate. In order to confirm the studies in vivo studies have to be conducted.

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Keywords

Buchanania axillaris Desr, Anthelmintic activity, Piperazine citrate.

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