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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 2
First page : ( 687) Last page : ( 689)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00129.4

Hypolipidemic activity of Alternanthera ficoidea Linn in Triton wr-1339 induced hyperlipidemic rats.

Sundarrajan T.1, Aanandhi M. Vijey2,*

1Research Scholar, Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels Institute of Science, Technology & Advanced Studies (VISTAS), Chennai, Tamilnadu, India

2Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science, Technology & Advanced Studies (VISTAS), Chennai, Tamilnadu, India

*Corresponding Author E-mail: hodpchemistry@velsuniv.ac.in

Online published on 12 June, 2018.

Abstract

The increased lipid profile is the greatest risk factor for atherosclerosis and other associated complications. Currently, available allopathy medicine has related to the number of side effects. Medicinal plants for hyperlipidemia has no side effects and is relatively inexpensive and locally available. The antihyperlipidemic activity of ethanolic extract of leaves of Alternanthera ficoidea Linn against Triton wr-1339 induced hyperlipidemia in rats. Alternanthera ficoidea Linn administered at a dose of 200mg/kg (p.o) to the triton induced hyperlipidemic rats. Alternanthera ficoidea Linn shows a significant decrease lipid profile levels like serum cholesterol, phospholipids, triglyceride, LDL, VLDL and the significant increase in the level of serum HDL level.

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Keywords

Alternanthera ficoidea Linn, Hyperlipidemia. LDL, VLDL, HDL.

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