Tea Poly Phenol-Zinc Oxide nano Particle effects on Infertile Smoker's Spermatozoa-A Short Report Balasundaram Sridharan1,*, Ranganathan Parameswari2, Rao Kamini A3 1Plant Biotechnology Lab, (National Tea Research Foundation Scheme), VIT University, Vellore, Tamil Nadu, India 2Gene Cloning and Technology Lab, Department of Bio Medical Sciences and Technology, VIT University, Vellore, Tamil Nadu, India 3Andrology Unit ART Medicine, Milann Hospital, Bangalore, Karnataka, India *Corresponding Author E-mail: tbsridharan@vit.ac.in
Online published on 12 June, 2018. Abstract Objective To evaluate the TPP-ZnO nano particle cyto toxic activity against smoking influenced spermatozoa Design An experimental study Setting Gene Cloning and Technology Lab, VIT University, Vellore Patient(s) Chronic smokers who came for first time for infertility issues Intervention(s) Tea poly phenol (TPP) mixed zinc oxide nanoparticle with smoker's semen against untreated control was analyzed. Main Outcome Measure(s) Spermatozoa motility, viability and appearance of morphology. Result(s) TPP mixed ZnO nano particle will give maximum (5%) of motility and MTT-IC50 shows the maximum viability (P<0.001) with positive morphological changes which near to untreated control. Conclusion(s) Metal toxicity from smoking effect on sperm motility and viability was reduced or improved with another natural antioxidant of TPP through ZnO nano delivery  Top Keywords Zinc oxide nano particle, Smoking, Cadmium, Tea poly phenol, ROS. Top |