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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 2
First page : ( 509) Last page : ( 512)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00093.8

A Prospective Study on Combinational Drug Efficacy in Hypertensive Patients

Yeswanthi S.*, Jayakumari S.

Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University, Chennai

*Corresponding Author E-mail: syeswanthi1994@gmail.com

Online published on 12 June, 2018.


Aim and Objectives

The main of aim of this study is to evaluate the combination drug efficacy in hypertensive patients and also reduction of blood pressure by using combination drugs.

Methods and Materials

This study which includes prospective monitoring of hypertensive patients who are taking different type of combination durgs to reduce blood pressure. This is prospective study done in hypertensive patients. The statistical method used in the study is student t test.


Totally 100 patients were included in the study. Three month was readings were taken. 1st month reading is taken as initial value and 3rd month reading is taken as final value. The baseline blood pressure was reduced from 171.2±3.2 to 137.1±2.6 in systolic blood pressure where as diastolic blood is reduced from 101.20±3.2 to 87.10±2.6 of patients using group D. The other group combinations also have slight changes in the reduction of blood pressure. The combination therapy shows greater efficacy in hypertensive patients.


The percentage reduction of blood pressure after using group D was more than compared with other combinations. This study concludes that combination drugs shows efficacy in hypertensive patients.



Atenolol +enalapril, telmisartan+perindopril, hypertension.


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