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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 2
First page : ( 429) Last page : ( 433)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00079.3

Effect of Potassium Dichromate on Ovary and Uterus in Female Mice

Hadi Abdul-Hadi Abbas1,*, Dohan Kareema Habeeb2

1Department of Laboratory Investigations, Faculty of Science, University of Kufa, Iraq

2Department of Biology, Faculty of Science, University of Kufa, Iraq

*Corresponding Author E-mail: abdulhadi.alibraheemi@uokufa.edu.iq

Online published on 12 June, 2018.

Abstract

The histopathological alterations in ovary and uterus were evaluated to investigate the possible effects ofhexavalent chromium as potassium dichromate (K2Cr2O7)in female albino mice. Forty-five adult female albino mice were used in this study. The mice treated orally with 500 and 1000 ppm of potassium dichromate that dissolved in tap water for 10, 20, and 30 days. The histologic examination by light microscope for the ovaries and uteri in potassium dichromate-treated mice revealed different histopathological alterations in these organs, whilst these organs of control groups exhibited a normal architecture. In addition, the results showed that the histological changes depend on the concentration and duration of exposure to potassium dichromate.

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Keywords

Potassium dichromate, Reproduction, Ovary, Uterus, Mice.

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