(34.229.119.176)
Users online: 1850    [ij] [ij] [ij] 
Email id
 

Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 12
First page : ( 5681) Last page : ( 5686)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.01029.6

Pharmacogenetics and Genetic Polymorphism of CYP Enzymes in Indian Population: A Clinical Review

Rajagopal Shanmuga Sundaram*, Varghese Anila A, Kandasamy Krishnaveni, Sukumaran Bhavatharini

Department of Pharmacology, Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Komarapalayam, Tamilnadu, India

*Corresponding Author E-mail: malshan34@gmail.com

Online published on 18 May, 2019.

Abstract

Pharmacogenetic polymorphism results from the mutations in a Cytochrome P450 (CYP) gene leading to functional alterations, such as increased or decreased activity and occurs at a frequency of at least one percent in a population. At present clinical situation drug clearance and inter-individual variation in drug response is a usual and complex problem. In this clinical review there is a fast update on pharmacogenetics and genetic polymorphism of CYP enzymes in Indian population.

Top

Keywords

CYP 450, Pharmacogenetics, Allele, polymorphism.

Top

  
║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
598,047,292 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.