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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 12
First page : ( 5543) Last page : ( 5647)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.01023.5

The Effects of Combined Exercise on Blood Lipids and Melatonin in Developmental Disorder Students

Son Chang-Min1, Min Bum-Il2,*, Moon Hyun-woong3

1First Autho Il-gok Middle School, 10, Ilgoktakji-ro, Buk-gu, Gwangju, Korea, 61040

2Nambu University, 23chumdan Jungang-ro, Gwangsan-gu, Gwangju, Korea, 62271

3Sang-mu High School, 28, Sangmu-ro 32beon-gil, Seo-gu, Gwangju, Korea, 61970

*Corresponding Author E-mail: littlebom71@naver.com, m7839@nambu.ac.kr, rider119@naver.com

Online published on 18 May, 2019.



Increased physical activity is important given the concern over the growing rates of obesity. In addition, exercise is based on previous studies that can provide treatment opportunities as well as prevention of depression and cognitive decline. The purpose of this study was to investigate effects of combined exercise on blood lipids and melatonin in developmental disorder students.

Methods/Statistical analysis

For this study, 7 developmental disorder students had been recruited and they participated combined exercise program which consisted of 8 exercises performed for 80mins a day, 3 times a week, at the intensity of HRmax (55∼60%) for 36 weeks. Blood sampling was performed before and after exercise during morning fast time. Blood analysis is associated with obesity total cholesterol (TC), Triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) and cognitive function related to melatonin. Mean and Standard Deviation were used for every variance through 21.0 SPSS Window Program. Paired t-test was used as the statistical analysis. Significance was accepted at p<.05.


This study found that combined exercise did have significant effects on HDL-C of blood lipids. But TC, TG, LDL-C and melatonin did not change significantly changed. In order to prevents obesity and cardiovascular disease with developmental disorder students. It is necessary to exercise intensity more than moderate intensity and exercise frequency three times a week.


In the case of severe developmental disorders. Exercise is important role in the lives of the disabled. The developmental disorder that participates in the regular exercise will improve athletic skills and fitness, while improving the social skills and fitness of others.



Obesity, Developmental disorder student, Combined exercise, Blood lipids, Melatonin.


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