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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 12
First page : ( 5551) Last page : ( 5558)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.01010.7

Comparison of Four Screening Methods for Diabetic Peripheral Neuropathy in Type 2 Diabetes Mellitus Patients: A Cross Sectional Study

Abraham M. Manoj1,*, Tyng Teh Shiueh2, Rekha K.3, Shanmugananth E4, Kiruthika S5

1Professor and Principal, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai

2BPT Student, Universiti Tunku Abdul Rahman, Malaysia

3Assistant Professor, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai

4Associate Professor, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai

5Tutor, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai

*Corresponding Author E-mail: manojpt3@gmail.com

Online published on 18 May, 2019.

Abstract

The diabetes situation in Malaysia is about 3.5 million or 17.5 per cent of its citizens aged 18 years and above are Diabetic. Diabetic peripheral neuropathy (DPN) is common and frequent cause of morbidity and disability. Early diagnosis and appropriate treatment are important to prevent disease complications, especially diabetic foot and ulceration. The aim of this research was to find out the prevalence of DPN, to determine which of the 4 screening methods (Michigan Neuropathy Screening Instrument (MNSI), Ankle Reflexes, 128-Hz Tuning Fork Test and 10-g Monofilament) was more reliable in screening for DPN and any correlation between them. A cross-sectional study with a random sample size of (N=81), type 2 diabetes mellitus participants in Diabetes Malaysia headquarters were screened for presence of DPN by using 4 different methods. Reliability and correlation between the 4 screening methods were calculated. The prevalence of DPN was 46.91% using MNSI. Prevalence of DPN using 10-g Monofilament test was highest (45.68%) and ankle reflexes were lowest (17.28%). Statistical significant associations were found between 10-g monofilament, MNSI Score, right and left ankle reflex, 128-Hz Tuning Fork Test on the right and left great toe. There was positive correlation between 4 screening methods and were reliable to be used to screen for DPN in type 2 diabetes mellitus patients. However MNSI and 10-g Monofilament test were more appropriate and reliable in screening for DPN.

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Keywords

MNSI, Diabetic Peripheral Neuropathy (DPN), ankle reflex, monofilament, Vibration test.

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