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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 12
First page : ( 5517) Last page : ( 5519)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.01004.1

In Vitro Anti Inflammatory Activity on the Ethanolic bark extract of Perseaamericana M.

Fernandes Zeena*

Ullas D’ Souzaand Prasanna Shama Khandige, Department of Pharmacology, N.G.S.M Institute of Pharmaceutical Sciences, Nitte (Deemed to be university), Paneer, Derlakatte, Mangaluru-575018

*Corresponding Author E-mail: zeena25@gmail.com

Online published on 18 May, 2019.

Abstract

Thepresent study was designed to evaluate the in vitro anti-inflammatory effect of the ethanolic extract of Perseaamericana bark against the denaturation of protein. The anti-inflammatory property of the extract was evaluated by preparing the extract at different concentrations and incubating it with egg albumin under controlled experimental conditions. Absorbance of the extract at different concentrations was determined by using reference drug as diclofenac sodium.. The present findings exhibited a concentration dependent inhibition of protein (albumin) denaturation by the Perseaamericana bark. From the present study it can be concluded that Perseaamericana bark possessed marked in vitro anti-inflammatory effect against the denaturation of protein.

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Keywords

Anti-inflammatory, Perseaamericana, Diclofenac sodium, Protein denaturation.

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