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Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 10
First page : ( 4667) Last page : ( 4670)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00853.3

Antidiarrhoeal activity of Peucedanum pastinacifolium in Rodents

Al-khazraji Shahbaa M.

Middle Technical University, Medical Technology Institute-Mansoor, Department of Pharmacy, Iraq

Corresponding Author E-mail:

Online published on 20 December, 2018.


The Anti-diarrhoeal effect of the aqueous extract of the aerial parts of in rosents was examined. At the doses of 125, 250, 500 mg/kg of the extract protected rats, in a dose increasing fashion against diarrhea promoted by castor oil dropping by38.09, 59.93 and 65.11% respectively. Further, it has significantly inhibited by 41.46% the gastrointestinal transit of charcoal in rats at 500 mg/kg dose of the extract. These data suggest that Peucedanum pastinacifolium shows antidiarrhoeal activity by inhibiting intestinal motility with no signs of acute toxicity which is correlated to its uses in folkloric medicine



Peucedanum pastinacifolium, antidiarrhoeal activity, intestinal transit, LD50.


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