Research Journal of Pharmacy and Technology
Year : 2018, Volume : 11, Issue : 10
First page : ( 4543) Last page : ( 4546)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2018.00831.4

Formulation and Evaluation of Ointment Containing Natural Wound Healing activity of Tridax procumbens

Deshmukh Rupali*, Agrawal Roshni, Chauragde Sarita, Lilhare Swati, Mrs. Mishra M. U.

Manoharbhai Patel Institute of Pharmacy (B. Pharm), Kudwa, Gondia

*Corresponding Author E-mail: Rupalideshmukh49@gmail.com

Online published on 20 December, 2018.

Abstract

Objectives-The main Objective of the work was to formulate and evaulate ointment of Tridax procumbens to analysis its wound healing activity. Methods-various phytochemicals were extracted solvent extraction using soxhlet apparatus and hydroalcholic extraction and these phytochemical were qualitatively analysed. Herbal ointment containing hydro alcholic leaf extract of Tridax Procumbens was formulated anddd tested for wound healing activites. The exteact was incorporated into ointment base by melting the two phase. Excision wound measuring about 7mm was created on depilated back of mice. Ointment formulation of Tridax Procumbens was applied twice daily for 15 day on the dermal wound. Blank ointment base and betadine served as control and standard respectively. Result-Topical application of hydroalcholic leaf extract of Tridax Procumbens incorporated into an ointment base and applied on the excision wound in mice caused significantly higher rate of wound healing and showed the highest rate of wound closure as compare to the blank ointment. Conclusion-We concluded that formulation and evaluaaation of ointment is effective in wound care and should be explored in harnessing the potential of plant in treatment of topical diseases.

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Keywords

Tridax procumbens, herbal ointment, wound healing, Excision wound, minimum inhibitory concentration.

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