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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 9
First page : ( 3185) Last page : ( 3187)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00566.2

Role of Interleukin 1 in Gingival Tissues in Chronic Periodontitis-A Review

Camabala Akansha Devandra, Gajendran Priyalochana*

Department of Periodontics, Saveetha Dental College, Saveetha University, Chennai, Tamil Nadu, India

*Corresponding Author E-mail: priyalochana.87@gmail.com

Online published on 16 May, 2018.


The diagnosis of active phases of periodontal disease and the identification of patients at risk for active disease pose a challenge for periodontist. Advances in oral and periodontal disease diagnostic research are progressing towards methods whereby periodontal risk can be identified and quantified by objective measures, such as biomarkers. IL-1 a potent cytokine, stimulates the proliferation of keratinocytes, endothelial cells and enhances fibroblast synthesis of type I procollagen, hyaluronate, and fibronectin. Therefore, IL-1 is a critical component in maintain the homeostasis of periodontal tissues. This review discusses the role of IL-1 in periodontitis.



Interleukin 1, Periodontitis, Gingiva.


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