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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 8
First page : ( 2784) Last page : ( 2792)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00493.0

Nanostructured Lipid Carrier (NLC): A Modern Approach for Transdermal Drug Delivery

Bornare A. S.1,*, Saudagar R. B.2

1Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India

2Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India

*Corresponding Author E-mail: ashwinibornare1993@gmail.com

Online published on 26 March, 2018.

Abstract

The primary objective of writing this article is to put the emphasis on the importance of nano structured based drug delivery systems. Although drugs as such can be delivered in the body using different routes but most of the routes esp. have its own limitations like poor solubility, absorption, first pass metabolism and poor bioavailability, hence need for this nanostructured based drug delivery systems was developed. This technique not only will help us in overcoming the above mentioned drawbacks but also this helps us in reducing the dose, systemic side effects and in addition to these, this also helps us in delivering the drugs to the site of action. These nano based systems can be used to deliver variety of drugs through different routes of administration including oral, topical, transdermal, ocular and parenteral. This review outlines the process involved in the preparation of NLC's, its characterization and evaluation and its pharmaceutical applications.

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Keywords

Nano-structured lipid carriers, Nanoparticle, Novel approach, Bioavailability, Targeted drug delivery.

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