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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 8
First page : ( 2517) Last page : ( 2521)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00445.0

Effects of Laparoscopic Mini Gastric Bypass (MGB) on Weight Loss and Biomarker Parameters in Morbidly Obese Patients: A 6-Month Follow-Up.

Najm Asawer Hasan*

Chemistry Department, Faculty of Sciences, University of Kufa, Iraq

*Corresponding Author E-mail: Asawer_h2010@yahoo.com

Online published on 26 March, 2018.

Abstract

Mini-gastric bypass is a bariatric surgical procedure prevalent in many focuses because of shorter length, simpler system, and fabulous weight reduction comes about. The point of this review was to assess the weight reduction and biomarker parameter changes amid 6-months time frame taking after MGB in Iraqi excessively fat patients. The study was conducted on 30 subjects (18 females and 12 males), age 34± 7.5 years, with BMI 51.7 ± 7.1 Kg/m2 presented for MGB during the period from July 2016 until the end of February 2017. FBG, HbA1c, total cholesterol, TG and HDL were measured before, 2 and 6 months after MGB procedure. Six months after surgery caused a significant reduction in body weight and BMI (p< 0.001). The mean weight of the participants decreased to 88.1 Kg, mean BMI decreased to 32.55 Kg/m2. The mean loss in the EBL percent was 74.6% and %WL was 34.9%. There was a significant reduction in FBG, HbA1c, cholesterol, TG, LDL and VLDL (p < 0.001). Meanwhile use of MGB procedure caused a significant increase in HDL level (p< 0.001).

Conclusion

MGB has all the earmarks of being a protected and compelling technique in extremely obese patients. Six month after strategy brings about weight reduction, lessening in obesity comorbidities, enhance glucose homeostasis and lipid profile, expanding HDL, and diminishing other measured biochemical parameters.

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Keywords

Bariatric surgery, Mini gastric bypass, Weight Loss, BMI, EBL%, lipid profile, HbA1c, Follow-up.

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