Utilization Pattern of Anti-Diabetic Drugs in Type 2 Diabetes Mellitus in Tertiary Care Hospital. Ms. Raphael Merry1, Dr. Vijayanarayana K2, Dr. Thunga Girish3, Dr. Rao N Karthik4, Dr. Sreedharan N2 1Student, Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka, India. 2Associate Professor, Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka, India. 3Assistant Professor, Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka, India. 4Assistant Professor, Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India. *Corresponding Author E-mail: vinpharmacol@hotmail.com
Online published on 17 October, 2017. Abstract Background Diabetes mellitus is a major public-health related problem. The increase in prevalence rates has led to an increase in the economic burden, worldwide. To manage the disease in a better way, Drug utilization research can be used as a strategy to justify the drug therapy. Aims To study the drug prescribing pattern of anti-diabetic drugs in newly diagnosed type 2 DM patients. Materials and methods A retrospective observational study was carried out in a tertiary care hospital. As per the study criteria, data was collected from medical records department (MRD) registry using ICD code E 11.9. Data was analysed using SPSS 20.0 and the DDD per 100 bed-days was calculated. Results A total of 662 patients were newly diagnosed with type 2 DM. The mean age of study population was 52.5 ± 12.5 years and 427(64.5%) patients were male. Hypertension was the most common comorbidity observed in 189 (28.5%) patients. Among the anti-diabetic drugs, the utilization of insulin (0.088 DDDs per 100 bed-days in 2013 and 0.16 DDDs per 100 bed-days in 2014) was highest and among the oral anti-diabetic drugs the utilization pattern of metformin (0.058 DDDs per 100 bed-days in 2013 and 0.071 DDDs per 100 bed-days in 2014) was the highest in both 2013 and 2014. Conclusion Biguanides (metformin) was highly prescribed anti-diabetic drug in both single and combination drug therapies. This study shows that the treatment pattern of type 2 DM patients is in accordance to the NICE (National Institute for Health and Clinical Excellence) guidelines. Top Keywords Anti-diabetic drugs, Biguanides, DDD per 100 bed-days, Diabetes mellitus, Drug utilization. Top |