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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 5
First page : ( 1509) Last page : ( 1516)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00266.9

Formulation aspects behind the development of a stable biphasic liquid dosage form with special reference to microemulsion

Gupta Shriya, Dhokne Sonali, Verma Rameshwar, Mitra Manish, Sahu Umesh, Bhardwaj Pitamber, Bhoyar Mohainish, Biswas Manoj, Sahu Lukesh, Jha Sheetal, Agrawal Mukta, Tripathi D. K.,  Ajazuddin, Alexander Amit*

Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, India, 490024

*Corresponding Author E-mail: itsmeamitalex@gmail.com

Online published on 17 July, 2017.

Abstract

Biphasic liquid dosage have an associated limitation of poor physical stability and therefore it is said to be thermodynamically unstable. Moreover, this area is also of great interest among the researchers towards the improvement of the stability. Thus, development of microemulsion systems is of great interest among the researchers. A microemulsion is a system of water, oil and amphiphilic compounds (surfactant and co-surfactant) which is a transparent, single opticalisotropic and thermodynamical stable liquid. Microemulsions are readily distinguished from normal emulsions by their transparency, low viscosity and more fundamentally their thermodynamic stability. In this review article, the various aspects of pharmaceutical microemulsion were compiled together and the target audiences are specifically the M. Pharm and B. Pharm students so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.

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Keywords

Microemulsion, transparency, amphiphilic.

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