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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 5
First page : ( 1491) Last page : ( 1496)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00263.3

The Relationship between Metabolic Factors and Quality of Life Aspects in Type 2 Diabetes Patients

Haidari Fatemeh1, Mansoori Esmat2,*, Zakerkish Mehrnoosh3, Haghighizadeh Mohammadhossein4

1Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2Nutrition Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

3Endocrinologist, Diabetes Research Center, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran

4Department of Biostatistics and Epidemiology, Faculty of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

*Corresponding Author E-mail: nut_mansoori@yahoo.com

Online published on 17 July, 2017.


Background and Objective

Quality of life (QoL) significantly influences the therapeutic outcomes in diabetic patients. The present study aimed to investigate the impacts of different aspects of QoL of patients with metabolic factors.


This cross-sectional descriptive study recruited 263 patients (mean age 51.79 years) with type 2 diabetes (T2D). Data were collected using demographic information form, the Persian version of the 36-item health-related QoL and Audit of Diabetes-Dependent Quality of Life (ADDQoL) questionnaires. Clinical and laboratory tests including total cholesterol, HDL-C and LDL-C were also performed. Statistical analysis was performed with statistical package SPSS version 22.0.


The mean total score of Diabetes Quality of Life (DQoL) was 53.54 ± 20.85 based on SF-36. The overall score of QoL showed a negative significant correlation with the levels of FBS, HbA1C and triglycerides (P<0.05). A statistically significant negative correlation was observed between physical health and total cholesterol levels, between mental health and QoL with FBS (P= 0.000), HbA1c (P= 0.001) and total cholesterol (P=0.024); however, no significant correlation was observed with other parameters.


Improvements in metabolic control have a significant effect on the Quality of Life among Adult T2D patients.



Audit of Diabetes-Dependent Quality of Life, Quality of Life, Type 2 Diabetic, Fasting Glucose, Lipid Profile, Glycosylated Hemoglobin.


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