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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 5
First page : ( 1305) Last page : ( 1312)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00231.1

Antidiabetic Activity and Toxicity Studies of Ethanolic Extract of Polialthia longifolia Roots

Johnson D. Benito*, Raj Akhil, Venkatanarayan R.

Department of Pharmacology, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore

*Corresponding Author E-mail: drbenitorvs@gmail.com

Online published on 17 July, 2017.

Abstract

Diabetic millets1 often referred to simply as diabetes (Ancient Greek: diabetes” to pass through [urine]”) is a syndrome of disorder metabolism, usually due to a combination of hereditary and environment causes, resulting in abnormally high blood sugar level (hyperglycemia). Diabetes is described as starvation in the midst of plenty. Because the body will have high amount of glucose level but the cells are incapable of consume it because of osmotic difference Insulin is a hormone produced in the pancreas, which enable body cells to absorb glucose, to turn into energy. If the body cells cannot absorb the glucose, the glucose accumulates in the blood (hyperglycemia), leading to acute metabolic complications including keto acidosis and in the long term contribute to chronic micro-vascular complications

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Keywords

Polialthia Longifolia, Subacute toxicity, Glibinclamide.

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