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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 4
First page : ( 1230) Last page : ( 1238)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00220.7

Pharmaceutical Considerations behind the Development and Evaluation of Mucoadhesive Tablets

Verma Rashmi, Dewangan Yamini, Sahu Lokeshwari, Dongre Barkha, Mishra Khushboo, Patel Trilok, Nishad Sakhram, Damle Ashish, Sahu Ghanshyam, DeviRao K., Mukta Agrawal MithleshPatle, Tripathi D. K., Ajazuddin, Alexander Amit*

Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, India, 490024

*Corresponding Author E-mail: itsmeamitalex@gmail.com

Online published on 17 July, 2017.

Abstract

The current article has been focused on the Mucoadhesive drug delivery system may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release for improved therapeutic outcome. Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Application of dosage forms to mucosal surfaces may be of benefit to drug molecules not amenable to the oral route, such as those that undergo acid degradation or extensive first-pass metabolism. The Mucoadhesive ability of a dosage form is dependent upon a variety of factors, including the nature of the mucosal tissue and the physicochemical properties of the polymeric formulation. This review article aims to provide an overview of the various aspects of mucoadhesion, Mucoadhesive materials, factors affecting mucoadhesion, evaluating methods, and finally various Mucoadhesive drug delivery systems (buccal, nasal, ocular, gastro, vaginal, and rectal) based on literatures were reported so far. In this review article, the various aspects of pharmaceutical microemulsion were compiled together and the target audiences are specifically the M. Pharm and B. Pharm students so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.

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Keywords

Bioadhesive, Transmucosal, absorption.

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