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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 4
First page : ( 986) Last page : ( 990)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00179.2

Free radical scavenging activity of Lyophilised Syzygium cumini (L) Skeels fruit pulp (Jamun)

Menaka M1,2,*, Venkatasubramanian Chandra3

1Research Scholar, Food and Nutrition, Bharathiar University, Coimbatore, India

2Dept of Clinical Nutrition and Dietetics, Ethiraj College for Women, Chennai, India

3Research Supervisor, Food and Nutrition, Bharathiar University, Coimbatore, India

*Corresponding Author E-mail: menamuthu@gmail.com

Online published on 17 July, 2017.

Abstract

Antioxidants are the compounds that can scavenge, prevent and terminate the free radical formation. In this study the free radical scavenging activity of Lyophilised Syzygium cumini (L) Skeels fruit pulp (Jamun) by enzymatic and non enzymatic assays like DPPH, ABTS, nitric oxide and super anion radical scavenging activity were reported. The LJP extract shows maximum inhibition for DPPH scavenging activity (62.3%/100μg/ml), ABTS radical scavenging activity (94.3%/100μg/ml), Nitric oxide scavenging activity (33.3%/100μg/ml), and super oxide radical scavenging activity (38.8%/100μg/ml) respectively. LJP extract shows stronger inhibition activity with an IC50 value for ABTS and DPPH radical scavenging activity at 63.43μg/ml and 39.8μg/ml concentration respectively. For the developing country like India, seasonal and low cost fruits like Jamun can play a pivotal role in micronutrient deficiency as well as disease prevention.

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Keywords

Antioxidants, DPPH, ABTS, Nitric oxide and superoxide anion.

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