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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 3
First page : ( 802) Last page : ( 810)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00152.4

A Numerical Simulation of Pressure Variation in Arteries affected by Stenosis

Dr. Bai H. Girija*

Department of Mathematics, Sathyabama University, Chennai-600 119, India

*Corresponding Author E-mail: girijanameprakash@gmail.com

Online published on 29 April, 2017.


This paper is mainly concerned with the effect of pressure variations in different dilations of stenotic arteries. In this study, we numerically analyzed unsteady blood flow in stenotic arteries with constrictions 25%, 50%, 75% and 90%. A finite volume method is used to investigate flow in a tube with an occlusion. Using computational fluid dynamics techniques, hemodynamic factors such as velocity, pressure and streamline patterns are investigated. Wall shear stress and strain are numerically analyzed. Results are compared and validated. The study of unsteady flow reveals correlation between regions of recirculation and the lesion's location. Detection and quantification of stenosis serve as the root for surgical interference. These techniques based on computer flow study are important for understanding the relationship between hemodynamic parameters and hazard of rupture.



Stenosis, Computational Fluid Dynamics, Hemodynamics, Numerical simulation, Finite Volume Method.


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