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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 3
First page : ( 792) Last page : ( 794)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00149.4

Antibacterial activity of Sodium Copper Chlorophyllin (SCC) from Leucas aspera L.

Rani Geetha R1,*, Banu N2

1Research Scholar, Department of Biotechnology, Vels Institute of Science Technology and Advanced Studies (VISTAS), Vels University, Chennai, Tamil Nadu, India

2Associate Professor, Department of Biotechnology, Vels Institute of Science Technology and Advanced Studies(VISTAS), Vels University, Chennai, Tamil Nadu, India

*Corresponding Author E-mail: rani.getu13@gmail.com

Online published on 29 April, 2017.

Abstract

Sodium copper chlorophyllin (SCC) belongs to a group of compound, porphyrins containing a chelated metal ion in the center of the molecule. It is a sodium salt containing copper as the central metal atom with loss of phytol chain. The present study was to extract the sodium copper chlorophyllin from Leucas aspera L. and to check its antibacterial activity. The results show that sodium copper chlorophyllin of Leucas aspera L. has significant anti-bacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi and Pseudomonas aeroginosa with Ampicillin (Std) 20 μg/ml as positive control. The active zone of inhibition was around 6–11 mm against the tested human pathogens. The Minimal Inhibitory Concentration (MIC) was determined and found to be around 31.2–125 μg/ml. This result confirms that the medicinal value of Leucas aspera L. of sodium copper chlorophyllin as an anti bacterial sources.

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Keywords

Medicinal plants, Sodium copper chlorophyllin (SCC), Pathogenic bacteria, Minimal inhibitory concentration (MIC), Leucas aspera L.

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