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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 2
First page : ( 562) Last page : ( 566)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00112.3

Assessment of Neurotoxicity of Cultivated Plants Grown in the Neighborhood of Industrial Regions of Central Kazakhstan

Konkabayeva Aiman*, Ishmuratova Margarita, Pudov Aleksandr, Bodeeva Rahat, Aitkulov Aidar, Tykezhanova Gulmira, Tyrzhanova Sayagul

E.A. Buketov Karaganda State University, Universitetskaya Str., 28, 100028, Karaganda, Republic of Kazakhstan

*Corresponding Author E-mail: science_365@yahoo.com

Online published on 29 April, 2017.


The article presents the results of the impact of cultivated plants grown in summer cottage areas of three industrial regions of Central Kazakhstan on the behavioral responses of rats. It was found that prolonged feeding (three months) with vegetables, grown in areas contaminated with heavy metals, caused inhibition of locomotor activity, exploratory activity, duration of freezing behavior and lack of visits to the center that is regarded as the increase of anxiety level of rats. The results showed inhibition of behavioral responses, that testifies of the neurotoxic effect of vegetables grown in the neighbourhood of industrial regions.



Heavy metals, behavioral responses, copper, cultivated plants, neurotoxicity, industrial regions.


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