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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 2
First page : ( 516) Last page : ( 524)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00103.2

Anti-Proliferative activity of Chlorophyllin from Phyllanthus Emblica L. against MCF-7 and Vero Cell line

Devi Durga M1,*, Banu N2

1Assistant Professor, Department of Biotechnology, Mohamed Sathak College of Arts and Science, Sholinganallur, Chennai-119

2Associate Professor, Department of Biotechnology, Vels Institute of Science Technology and Advanced Studies (VISTAS), Vels University, Pallavaram, Chennai

*Corresponding Author E-mail: durgamani87@gmail.com

Online published on 29 April, 2017.

Abstract

Chlorophyllin refers to any one of a group of closely related water-soluble salts that are semi-synthetic derivatives of chlorophyll. It is most common form is sodium copper derivative used as a food additive and in alternative medicine. In this study sodium copper chlorophyllin was extracted from Phyllanthus emblica, a medicinal plant and estimated by visible spectrophotometer and further characterized by TLC, IR, NMR and GC-Mass Chromatographic techniques and studied the anticancer activity against MCF-7 cell line and Vero cell line. Result shows that Chlorophyllin of Phyllanthus emblica has good anticancer activity for breast cancer cell line by using MTT assay.

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Keywords

Chlorophyllin, Thin Layer Chromatography, MTT assay.

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