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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 12
First page : ( 4467) Last page : ( 4470)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00824.1

A Review on Antidiabetic Activity of Substituted 1, 3, 4-Thiadiazole Derivatives.

Vaishnav Yogesh1,*, Jha Arvind Kumar1, Verma Shekhar1, Kashyap Pranita2, Kaur Chanchal Deep2

1SSTC-SSGI-Faculty of Pharmaceutical Sciences, Bhilai, Chhattisgarh, 490020, India

2Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg, Chhattisgarh, 490042, India

*Corresponding Author E-mail: yogesh446688@gmail.com

Online published on 26 March, 2018.

Abstract

1, 3, 4 thiadiazole is considered to be an important heterocyclic nuclei which possesses wide variety of biological activity such as anticancer, anti-inflammatory, antimicrobial, antihypertensive, antifungal, antidiuretic and antidiabetic. Modification and substitution on thiadiazole ring minimizes the toxicity with improved activity. Present review highlights the recent research findings on 1, 3, 4 thiadiazole nucleus for antidiabetic activity. The information highlighted in this review acts as important gestalt for researchers to build a novel chemical entity owning antidiabetic activity.

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Keywords

Diabetes, 1, 3, 4 thiadiazole derivatives, Antidiabetic activity, Anticancer, Antimicrobial.

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