A Review on Antidiabetic Activity of Substituted 1, 3, 4-Thiadiazole Derivatives.
Vaishnav Yogesh1,*, Jha Arvind Kumar1, Verma Shekhar1, Kashyap Pranita2, Kaur Chanchal Deep2
1SSTC-SSGI-Faculty of Pharmaceutical Sciences, Bhilai, Chhattisgarh, 490020, India
2Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg, Chhattisgarh, 490042, India
*Corresponding Author E-mail: email@example.com
Online published on 26 March, 2018.
1, 3, 4 thiadiazole is considered to be an important heterocyclic nuclei which possesses wide variety of biological activity such as anticancer, anti-inflammatory, antimicrobial, antihypertensive, antifungal, antidiuretic and antidiabetic. Modification and substitution on thiadiazole ring minimizes the toxicity with improved activity. Present review highlights the recent research findings on 1, 3, 4 thiadiazole nucleus for antidiabetic activity. The information highlighted in this review acts as important gestalt for researchers to build a novel chemical entity owning antidiabetic activity.
Diabetes, 1, 3, 4 thiadiazole derivatives, Antidiabetic activity, Anticancer, Antimicrobial.