Exfoliative Cytology: A Globally Dependable Diagnostic Methodology for Pathologists-A Review Murugan Krishnaveni1, Dr. Aravindhan R.2, Dr. Kumar M. Sathya2, Dr. Sivachandran A.2, Dr. Magesh K.T.2 1CRI Student, SRM Kattankulathur Dental College, Potheri 2Department of Oral Pathology, SRM Kattankulathur Dental College, Potheri Corresponding Author E-mail: jayaprakashvel@gmail.com
Online published on 26 March, 2018. Abstract “Exfoliative cytology” as the name suggests (cyto=cells; logy=study) is the study of cells that exfoliate or wither into the body cavities. In a normal epithelium, superficial layers undergo constant exfoliation which is considered as a normal physiological process and deeper layers of the epithelium are always strongly intact. In case of a pathological condition or presence of a lesion, deeper layers of epithelium loses its cohesive force and undergoes exfoliation along with superficial cells (1). A study of these exfoliated cells is called “exfoliative cytology”. Exfoliative cytology is a simple, easy and rapid technique and a bloodless non invasive procedure that can be conducted multiple number of times (2). This methodology was first discovered by George Nicholas Papanicolaou(1883–1962) that is used till date in diagnosis of simple to complicated malignant and premalignant lesions that is helping pathologists all over the world. Top Keywords Dysplastic changes, Exfoliative cytology, Malignant and premalignant lesions, Oral mucosa, Smokers. Top |