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Research Journal of Pharmacy and Technology
Year : 2017, Volume : 10, Issue : 1
First page : ( 346) Last page : ( 350)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2017.00070.1

A Complexity Focus on Nanotoxicology-A Review

Subhashini V1,*, Bhojraj Suresh1, Prakash Keshav S2, Shalilni T2

1Department of Pharmacology, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, India

2Professor of, Pharmacology, JSS University, Mysore

3Sri Ramachandra University, Chennai

*Corresponding Author E-mail: subhavedagiri@hotmail.com

Online published on 29 April, 2017.


This article will discuss some of the general considerations on the complexity of Nanotoxicology (NT). The real scope of Nanotoxicology involves many processes. Nanotoxicology is an emerging discipline evolving from studies of ultrafine particles called the nano-particles (NP). The small size facilitates uptake into cells and transcytosis across epithelial and endothelial cells into the blood and lymph circulation to reach potentially sensitive target sites such as bone marrow, lymph nodes, spleen, and heart. Access to the central nervous system (CNS) and ganglia via translocation along axons and dendrites of neurons, evidences of mitochondrial distribution and oxidative stress response after NSP endocytosis point to a need for basic research on their interactions with subcellular structures.



Nanotoxicology (NT), Nano particles (NP), Nano sized particles (NSP), Central nervous system (CNS).


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