Personalized Medicine-A Novel approach in Cancer Therapy Swapnaa B, Kumar Santhosh V* Department of Pharmacology, School of Pharmaceutical Sciences, Vels University, Chennai, India *Corresponding Author E-mail: natu_sea@hotmail.com
Online published on 29 April, 2017. Abstract The word"personalized medicine" wasregularlylabelled as providing patient withtheright drug at the right dose at the right time. Personalized medicine was being advanced through data from the Human Genome Project. Cancer was a disease of the genome. In cancer, different tumours may have the same DNA, but the gene expression pattern was different in different tumour types. Genomic variations in EGFR and ERCC1 have been correlated with drug response in small cell lung cancer patients, HER2, BRCA1 in breast cancer. The isolation and analysis of CTCs may be a useful method for tracking how cancers evolve during therapy. Personalized medicine was receiving a large amount of growing attention for its tremendous potential with new opportunities. Top Keywords Personalized medicine, Cancer, Human genome project, Personal ‘omics’ profile, Circulating tumour cells, Precision oncology. Top |