Hepatoprotective Activity of Stem Bark of Nyctanthes arbor-tristis linn Tripathi Vaibhav1,, Kujur Adeep2, Dr. Saluja Manmeet Singh3 1Columbia College of Pharmacy, Raipur-493111, C.G., India 2University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur-492010, C.G., India 3TIT College of Pharmacy, Bhopal-462001, M.P., India *Corresponding Author E-mail:
Online published on 29 October, 2015. Abstract The present study is to evaluate the hepatoprotective effects of the 50% hydro-ethanol (Heena) extracts of stem bark of Nyctanthes arbor-tristis linn, against paracetamol induced hepatotoxicity in rats. The hepatoprotective effects of HEENA (500 mg/kg) was estimated by liver function test and serum profile. The results revealed that the extract of selected plant produce significant hepatoprotective effect not only by decreasing serum transaminase (SGPT and SGOT), alkaline phosphate and total bilirubin, but also significantly increased the levels of serum proteins (albumin, fibrinogen haeptoglobin, ceruloplasin, transferring etc). The effects of Heena was comparable with standard drug silymarin. Top Keywords Hepatotoxicity; Nyctanthes arbor-tristis linn; Heena; SGPT; SGOT. Top |