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Research Journal of Pharmacology and Pharmacodynamics
Year : 2015, Volume : 7, Issue : 1
First page : ( 19) Last page : ( 22)
Print ISSN : 0975-4407. Online ISSN : 2321-5836.
Article DOI : 10.5958/2321-5836.2015.00004.X

Prescribing Trends of Antidiabetic Fixed dose combinations in a rural tertiary care teaching hospital in Central India: An Observational, cross-sectional study

Santra Diptendu*, Totade Sangita

J.N. Medical College, Sawangi (M), Wardha (Maharashtra)

*Corresponding Author E-mail: diptendusantra@gmail.com

Online published on 2 May, 2015.



To assess prescribing trends of Fixed dose combination antidiabetics in Diabetes Mellitus patients.

Materials and Methods

An observational, cross-sectional study was carried out in the Medicine OPD of AVBRH, Sawangi(M), Wardha. A total of 500 Diabetes Mellitus Patients were selected for the study after fulfilling the inclusion/exclusion criteria.


Out of 500 patients 484 patients were of type-II DM in whom 5 FDCs were prescribed. Maximum prescribed FDCs were of Metformin and sulfonylurea Metformin + Glimepiride (n=74) and Metformin + Glipizide (n=37). Following FDCs were Metformin + Voglibose (n=52), Glimepiride + Pioglitazone (n=18) and least prescribed was Metformin+ Glimepiride + Voglibose (n=10). All the drugs were prescribed by brand names. Total of 191 patients (39.46%) were prescribed Antidiabetic FDCs.


All Antidiabetic FDCs prescribed were rational. FDCs in Antidiabetics are useful in combination therapy for increasing patient compliance and achieving euglycemia more effectively.



Prescribing trends, Diabetes Mellitus, Fixed dose combinations.


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